Soften the cream cheese at room temperature for about 30 minutes.
In a mixing bowl, combine softened cream cheese and grated sharp cheddar cheese.
Add beer, Dijon mustard, Worcestershire sauce, garlic powder, onion powder, and season with salt and pepper.
Mix all ingredients thoroughly until smooth and well-combined.
Taste the mixture and adjust seasonings if necessary.
Transfer to an airtight container and refrigerate for at least an hour before serving.
Serve chilled with assorted dippers such as pretzels, crackers, or vegetable sticks.