Preheat the air fryer to 400°F (200°C).

Prepare the fish by cutting it into bite-sized pieces.

In a bowl, combine panko breadcrumbs, chili powder, garlic powder, cumin, salt, and pepper.

Dip each fish piece into the breadcrumb mixture, ensuring they are well-coated.

Spray the air fryer basket with cooking spray to prevent sticking.

Place the coated fish pieces in the air fryer basket in a single layer.

Air fry for 10 minutes, shaking the basket halfway through.

Warm the corn tortillas in a pan or microwave.

Assemble the tacos by placing the crispy fish in the tortillas.

Serve with lime wedges on the side.